Blanding av Sobril med alkohol eller andre dempende stoffer øker risikoen for paradoksalvirkninger. Du kan blant annet oppleve at du blir mye fortere og mer entire enn du blir ellers. Overdosefaren øker også vesentlig dersom du blander Sobril med alkohol eller andre dempende stoffer/legemidler. Dette legemidlet er skrevet ut kun til deg. Ikke

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I en kommentar fra en pasientrepresentant i komitéen, Lucy Ryan, understrekes det at denne retningslinjen kan bidra til mer konsistens i behandlingen og støtten til personer med kronisk smerte. I denne studien har forskerne gjort en systematisk gjennomgang av tidligere oversikter for å undersøke effekten av antidepressiva mot kroniske smerte